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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Tony Willis | 131 | 2054-2058 | |
| 2 | Manuel Luján | 94 | 2039-2056 | |
| 3 | Ernie Ferguson# | 86 | 2062-2064 | |
| 4 | José González# | 76 | 2061-2064 | |
| 5 | Wilson De Jesús | 68 | 2034-2037 | |
| 6 | Xin Huang# | 66 | 2060-2062 | |
| 7 | Sean Bannatyne# | 65 | 2054-2064 | |
| 8 | Jim Barker# | 64 | 2056-2059 | |
| 8 | Bill Gamble# | 64 | 2059-2064 | |
| 8 | José Sánchez | 64 | 2026-2032 | |
| 11 | Melvin Miller# | 60 | 2060-2063 | |
| 12 | Maikel Koudstaal | 57 | 2045-2059 | |
| 13 | Dave Keys | 55 | 2039-2049 | |
| 14 | Eric Coleman | 51 | 2045-2056 | |
| 14 | Hsueh-liang Yep# | 51 | 2059-2064 | |
| 16 | Odílio Barca | 50 | 2038-2054 | |
| 16 | Jorge Guerra# | 50 | 2058-2064 | |
| 16 | Andrew Irwin | 50 | 2045-2053 | |
| 16 | Jim McNeilly# | 50 | 2063-2064 | |
| 16 | Travis Turner | 50 | 2050-2062 | |
| 21 | Vicente García | 49 | 2047-2058 | |
| 21 | Robby Matthews# | 49 | 2060-2063 | |
| 23 | Jai Blanksby | 48 | 2027-2031 | |
| 23 | César Fernández | 48 | 2038-2041 | |
| 23 | Brent Lynn# | 48 | 2058-2062 | |
| 23 | Denny Powell | 48 | 2050-2057 | |
| 27 | Alejandro Hernández | 47 | 2037-2046 | |
| 27 | Jeff Wright | 47 | 2042-2052 | |
| 29 | Anthony McAuslan# | 46 | 2063-2064 | |
| 29 | Stephen Randolph# | 46 | 2052-2054 | |
| 31 | Mark Armstrong# | 45 | 2061-2063 | |
| 32 | Danny Cole | 44 | 2028-2033 | |
| 32 | Jason Dunbar | 44 | 2035-2037 | |
| 34 | Charles Butler | 43 | 2046-2048 | |
| 34 | Manuel Costa# | 43 | 2058-2061 | |
| 34 | Craig Dillard | 43 | 2044-2047 | |
| 34 | Jassiem Jr.Murimi | 43 | 2033-2043 | |
| 38 | John Quintana# | 42 | 2062-2063 | |
| 38 | Matt Ruffin# | 42 | 2061-2063 | |
| 38 | Joe Ward# | 42 | 2052-2054 | |
| 41 | Víctor Peña | 41 | 2053-2062 | |
| 42 | Bartolo Delgado | 40 | 2025-2026 | |
| 42 | Chet English# | 40 | 2058-2060 | |
| 42 | Jose Fresno | 40 | 2024-2025 | |
| 42 | José Hernández# | 40 | 2062-2064 | |
| 42 | Carlos Payne | 40 | 2036-2041 | |
| 47 | Manny Arroyo# | 39 | 2062-2064 | |
| 47 | Robert Perkins | 39 | 2024-2027 | |
| 47 | Luis Rodríguez# | 39 | 2060-2062 | |
| 50 | Paul Ashe | 38 | 2043-2044 | |
| 50 | Freddy Blandin# | 38 | 2057-2061 | |
| 50 | Donnie Cantrell | 38 | 2046-2051 | |
| 50 | Michael Carver# | 38 | 2060-2064 | |
| 50 | Luis Manuel Hernández | 38 | 2044-2048 | |
| 50 | Jeff McParland# | 38 | 2053-2056 | |
| 50 | António Sánchez# | 38 | 2049-2054 | |
| 50 | Carlos Trujillo# | 38 | 2056-2064 | |
| 58 | Steve Bell | 37 | 2041-2054 | |
| 58 | Ted Erickson | 37 | 2040-2041 | |
| 58 | Bruce Ernst | 37 | 2042-2052 | |
| 58 | Kevin Godwin | 37 | 2047-2049 | |
| 58 | Emílio Gómez | 37 | 2050-2053 | |
| 58 | Adam Hammond | 37 | 2030-2042 | |
| 58 | John Martínez | 37 | 2044-2047 | |
| 58 | Luis Miguel Ruíz# | 37 | 2056-2057 | |
| 58 | Hossam Tantawi# | 37 | 2055-2062 | |
| 67 | Travis Banda | 36 | 2043-2052 | |
| 67 | Leonard Brown | 36 | 2048-2054 | |
| 67 | Ramón Esquivel | 36 | 2037-2040 | |
| 67 | Orlando Ramírez# | 36 | 2060-2062 | |
| 71 | Javier Hernández# | 35 | 2059-2063 | |
| 71 | Dave Reed | 35 | 2031-2043 | |
| 71 | Arden Tregre | 35 | 2024-2026 | |
| 71 | Alfredo Trevino | 35 | 2036-2040 | |
| 71 | Robinson Trujillo | 35 | 2047-2053 | |
| 76 | Carlos Benítez | 34 | 2042-2045 | |
| 76 | Michael Bridgewater# | 34 | 2062-2064 | |
| 76 | Joe Brown | 34 | 2043-2045 | |
| 76 | Ben Carlson | 34 | 2048-2050 | |
| 76 | Enrique Féliz# | 34 | 2058-2062 | |
| 76 | Gerald Glenn | 34 | 2048-2061 | |
| 76 | Brady Hebert | 34 | 2039-2041 | |
| 76 | Luo-shan Li# | 34 | 2062-2064 | |
| 76 | Kyle Morrison | 34 | 2060-2061 | |
| 76 | Jeff Robles# | 34 | 2055-2058 | |
| 76 | Tim Rodríguez | 34 | 2053-2054 | |
| 87 | Lewis Farris | 33 | 2053-2057 | |
| 87 | Dave Hopkins | 33 | 2042-2044 | |
| 87 | Sergio Medina | 33 | 2052-2053 | |
| 87 | Carlos Toledo# | 33 | 2057-2064 | |
| 87 | Su-gyung Yi | 33 | 2051-2054 | |
| 92 | Wesley Brear# | 32 | 2060-2064 | |
| 92 | Tomás Caballero# | 32 | 2061-2064 | |
| 92 | Alexandre Corré# | 32 | 2056-2059 | |
| 92 | Fletcher Craig | 32 | 2042-2044 | |
| 92 | Dave Harris# | 32 | 2062-2064 | |
| 92 | Pedro Hernández | 32 | 2034-2045 | |
| 92 | Roberto Hernández# | 32 | 2061-2064 | |
| 92 | Pablo Morán# | 32 | 2059-2064 | |
| 92 | Melvin Taylor | 32 | 2046-2048 |
