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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saito, Kiyohisa | LF | East St. Louis Eagles | 21 | 11/27/2050 | Musashino | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Salas, Jesús | RP | Montreal Whiz | 26 | 12/19/2045 | Maracaibo | VEN | Left | Right | 6' 0" | 190 lbs | - |
| Salgado, Will | LF | George Town Tourists | 23 | 06/25/2049 | Grandville | USA | Left | Left | 6' 1" | 190 lbs | - |
| Salmerón, Francisco | 1B | Sing Sing Songbirds | 26 | 10/12/2046 | Brookline | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sanders, Keith | RF | Sing Sing Songbirds | 25 | 03/10/2047 | Santa Rosa | USA | Left | Left | 5' 9" | 180 lbs | - |
| Schroeder, Rick | RF | Crab Apple Sluggers | 26 | 08/19/2046 | Milwaukee | USA | Right | Right | 6' 1" | 200 lbs | - |
| Schur, Lou | SP | Sing Sing Songbirds | 24 | 11/13/2047 | Los Angeles | USA | Right | Right | 6' 10" | 205 lbs | - |
| Searle, Chris | SS | Free Agent | 23 | 07/22/2049 | Thunder Bay | CAN | Right | Right | 6' 1" | 170 lbs | - |
| Serrano, Juan | SP | Hell HellFire | 24 | 05/17/2048 | Forest Lake | USA | Right | Right | 5' 9" | 170 lbs | - |
| Shepard, Dylan | CL | Puerto Vallarta Freedom | 34 | 04/28/2038 | Brooklyn | USA | Right | Right | 6' 1" | 200 lbs | - |
| Simmons, Rich | C | Jackson Hole Bucks | 23 | 05/15/2049 | Amsterdam | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sinha, Oscar | SP | Wildwood Waves | 26 | 02/24/2046 | Jacksonville | USA | Right | Right | 6' 6" | 205 lbs | - |
| Skillenaer, Nathan | SP | Lake Champlain Monsters | 23 | 04/14/2049 | Plano | USA | Right | Right | 6' 4" | 200 lbs | - |
| Smallwood, Tommy | 1B | Minneapolis Mud Hens | 23 | 10/19/2049 | Nanaimo | CAN | Left | Left | 6' 1" | 200 lbs | - |
| Smith, Gordon | 3B | Granville Greyhounds | 21 | 05/05/2051 | Paducah | USA | Right | Right | 6' 1" | 190 lbs | - |
| Smith, Pete | CF | Minneapolis Mud Hens | 22 | 09/15/2050 | Mobile | USA | Right | Right | 6' 2" | 185 lbs | - |
| Snape, Severus | SP | Summit County Soap Box Derby | 21 | 04/16/2051 | Mesa | USA | Left | Right | 6' 6" | 195 lbs | - |
| Snyder, Allen | SS | Bridgetown Buccaneers | 25 | 09/19/2047 | Black River Falls | USA | Right | Right | 5' 10" | 170 lbs | - |
| So, Sung-yong | RP | Lexington Platinum | 25 | 05/21/2047 | Seoul | KOR | Right | Right | 6' 4" | 215 lbs | - |
| Solíz, Francisco | SP | Lake Champlain Monsters | 23 | 01/30/2049 | Muskegon Heights | USA | Left | Right | 6' 0" | 180 lbs | - |
| Souza, Wesley | SP | Crab Apple Sluggers | 27 | 07/26/2045 | Bayamón | PUR | Left | Right | 5' 11" | 200 lbs | $273,000 |
| Spivey, Caden | RP | Montreal Whiz | 26 | 03/16/2046 | Garner | USA | Right | Right | 6' 3" | 200 lbs | - |
| Stamatelopoulos, Eustace | SS | Minneapolis Mud Hens | 23 | 12/28/2048 | Alexandria | GRE | Right | Right | 6' 0" | 185 lbs | - |
| Stanton, Charles | SP | Olympic River Swimmers | 23 | 12/14/2048 | Winchester | USA | Left | Right | 5' 9" | 190 lbs | - |
| Stewart, Earl | SP | Jasper Mom & Pops | 22 | 11/24/2049 | Fairfield | USA | Left | Right | 6' 4" | 200 lbs | - |
| Stone, Jerry | SP | Puerto Vallarta Freedom | 26 | 12/29/2045 | Rialto | USA | Left | Right | 6' 1" | 195 lbs | $273,000 |
| Strong, Bob | 1B | Brainerd Seagulls | 33 | 09/15/2039 | Wichita | USA | Left | Left | 5' 11" | 200 lbs | - |
| Summers, Karl | LF | East St. Louis Eagles | 23 | 03/06/2049 | Towson | USA | Left | Left | 6' 1" | 195 lbs | - |
| Sánchez, Adrián | SP | St. Augustine Crusade | 25 | 03/02/2047 | Morelia | MEX | Left | Right | 6' 7" | 200 lbs | - |
| Sánchez, Adrián | 3B | Green Bay Huskies | 26 | 11/07/2045 | Novato | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Armando | 3B | Lexington Platinum | 26 | 03/14/2046 | Parker | USA | Right | Right | 5' 9" | 195 lbs | - |
| Sánchez, Juan Jose | 2B | Lake Champlain Monsters | 25 | 01/17/2047 | Mexico City | MEX | Right | Right | 6' 3" | 200 lbs | - |
| Sánchez, Pancho | 2B | Green Bay Huskies | 23 | 01/19/2049 | Alajuela | CRC | Left | Right | 6' 3" | 180 lbs | - |
